Publications

List of Publications (* Corresponding Author)

  1. Amarnath Singam, Calvinique Lee, Dongyoung Kim, Jennifer Zheng, Jingchun Chen, Jeong Hee Kim, Jaeyun Moon, Roman Shugayev, Seungman Park*, “Holotomography-based quantification of intracellular viscosity using nanodiamonds containing nitrogen-vacancy (NV) centers” ACS Applied Nano Materials, 2026, Accepted
  2. Jeong Hee Kim, Lina R Nih, Seungman Park* “Cellular Viscous Properties in Senescence: An Emerging Biophysical Perspective and Potential Biomarker ” Ageing Research Reviews, 2026, 103255
  3. Richard M Oxborough, Trishan Wickramasinghe, Nikita Gopakumar, Michael Fong, Abdul Rahim Mohammed Sabtiu, Whitney A Qualls, Joseph W Diclaro, Jaslyn Stamey, Rui-de Xue, Yafet Tiruha, Thomas S Churcher, Seungman Park, Yaw Afrane, Louisa A Messenger, “Portable experimental hut tents (PEHTs): a conceptual framework for improved malaria vector control decision-making with a review of fixed experimental hut sites in Africa” Parasites & Vectors, 2026, Accepted
  4. Sunjeet Saha, Amarnath Singam, Melanie White, Colbey Kimbel, Nikita Gopakumar, Jeong Hee Kim, Jingchun Chen, Ashkan Salamat, Seungman Park*, “Holotomography-Based, Label-Free Quantification of Cellular Dry Mass as a Biophysical Indicator of Microglial Aβ Phagocytosis during Senescence” Biogerontology, 2026, 27 (2), 77
  5. Kim Jaechang, Son Inwoo, Vesper Evereux, Vivekanandan Subramanian, Daniel Kolpek, James Ogidi, Seungman Park, Yongdoo Park, Jonghyuck Park, “Molecular Weight-Driven Tunable Hyaluronic Acid-Based Hydrogels Modulate Immune Polarization in Three-Dimensional Microenvironments” ACS Biomaterials Science & Engineering, 2026, 12 (4), 2173-2188
  6. Sujan Chetterjee, Nguyen Tran, Loretta Vierra, Zachary Sin, Kevin Ritter, Xue Bessie Su, Saharat Jolak Ragsac, Seungman Park, Qian Liu, Adolfo Saiardi, Henning Jessen, Tam Tran, George Koshkaryan, Richard Van, Mira Han, Katherine Huang, Kayci Huff-Hardy, Richard Rood, Anas Gremida, Martin Gregory, Chien-Huan Chen, Parakkal Deepak, Anuj Shukla, Prasun Guha, “Phytic Acid (InsP6) Activates HDAC3 Epigenetic Axis to Maintain Intestinal Barrier Function” Nature Communications, 2026, 17 (1), 4770
  7. Nikita Gopakumar, Huang Chen, Louisa Messenger*, Seungman Park*, “Influence of Biophysical and Biochemical Cues on Plasmodium Sporozoite Dynamics in Skin Tissue” Parasites & Vectors, 2025, 18 (1), 1-12
  8. Mohammad Fazlul Haque, Seungman Park, Daejong Yang, “Gas Sensors in Harsh Environments: Challenges and Advances in High Temperature, High Humidity, Radiative and Corrosive Conditions” Journal of Science: Advanced Materials and Devices, 2025, 101049
  9. Ivan Isaac, Luv Patel, DongSoo Yun, Seungman Park, Chandrabali Bhattacharya, “Endogenous Corticosteroid Derived Lipid Nanoparticles (Cortico LNPs) Enable Selective mRNA Delivery to the Spleen” Small, 2025, e03034
  10. Calvinique Lee, Avinash Yaganapu, Amarnath Singam, Stephanos Fikru, Reza Rahmani, Jennifer Zheng, Mingon Kang*, Seungman Park*, “Artificial intelligence in cellular senescence research” Aging Advances, 2025, 2(4):147-154
  11. Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya, “Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas” Advanced Materials, 2025, 2507657
  12. Amarnath Singam, Nikita Gopakumar, Apoorva Chauhan, Kimberly Ramirez, Jeong Hee Kim, Chandrabali Bhattacharya, Jingchun Chen, Deok-Ho Kim, Seungman Park*, “Unveiling Lipid Droplet Transport Dynamics as Biomarkers of Senescence Using Label-Free, Time-Lapse Holotomography” Aging and Disease, 2025, 17:1-17
  13. Jeong Hee Kim, Daejong Yang, Seunman Park*, “Raman Spectroscopy in Cellular and Tissue Aging Research” Aging Cell, 2025, e14494, 1-17.
  14. Vesper Evereux, Sunjeet Saha, Chandrabali Bhattacharya, Seungman Park*, Characterization of time-dependent viscoelastic behaviors of alginate-calcium chloride hydrogels for bioprinting applications” Biomedical Engineering Letters, 2025
  15. Ivan Isaac, Altab Shaikh, Mayurakkhi Bhatia, Qian Liu, Seungman Park, Chandrabali Bhattacharya, “Tetrahydropyrimidine Ionizable Lipids for Efficient mRNA Delivery” ACS Nano, 2024, 18 (42), 29045-29058
  16. Amarnath Singam, Chandrabali Bhattacharya, Seungman Park*, “Aging-related changes in the mechanical properties of single cells” Heliyon, 2024, e32974:10:12
  17. Jeong Hee Kim, Daejong Yang, Seungman Park*, “Experimental validation for the interconversion between generalized Kelvin–Voigt and Maxwell models using human skin tissues” Journal of Biomechanics, 2023, 162, 111908
  18. Seungman Park*, Thomas C. Laskow, Jingchun Chen, Prasun Guha, Buddhadeb Dawn, Deok-Ho Kim*, “Microphysiological Systems for Human Aging Research” Aging Cell, 2023, e14070: 1-25. (Top viewed article in 2024)
  19. Jingchun Chen, Lingyun Xu, Xindi Li, Beiyu Lin, Seungman Park*, “Deep Learning Models for Cancer Stem Cell Detection: A Brief Review” Frontiers in Immunology, 2023, 14, 1214425
  20. Seungman Park*, Anna L. Chien, Isabelle D. Brown, Jingchun Chen, “Characterizing viscoelastic properties of human melanoma tissue using Prony series” Frontiers in Bioengineering and Biotechnology, 2023, 11, 475
  21. Seungman Park*, Anna L. Chien, Beiyu Lin, Keva Li, “FACES: A Deep-Learning-Based Parametric Model to Improve Rosacea Diagnoses” Applied Sciences, 2023, 13:2, 970
  22. Seungman Park*, Byunggik Kim, “Aging-related structural changes in 3D extracellular matrix affects its mechanics” Medical Engineering & Physics, 2022, 106, 103843
  23. Matthew Pittman, Ernest Iu, Keva Li, Mingjiu Wang, Junjie Chen, Nilay Taneja, Myung Hyun Jo, Seungman Park, Wei-Hung Jung, Le Liang, Ishan Barman, Taekjip Ha, Stavros Gaitanaros, Jian Liu, Dylan Burnette, Sergey Plotnikov, Yun Chen, “Membrane Ruffling is a Mechanosensor of Extracellular Fluid Viscosity” Nature Physics, 2022, 1-10
  24. Seungman Park*, “Biochemical, structural and physical changes in aging human skin, and their relationship” Biogerontology, 2022, 1-14. (Averaged ~30 citations per year)
  25. Gaofeng Wang, Evan Sweren, Haiyun Liu, Eric Wier, Martin P. Alphonse, Nasif Islam, Ang Li, Yingchao Xue, Ruosi Chen, Junjie Chen, Seungman Park, Yun Chen, Sam Lee, Yu Wang, Nate K. Archer, William Andrews, Maureen Kane, Erika Dare, Zhiqi Hu, Elizabeth A. Grice, Lloyd S. Miller, Luis Andres Garza, “Bacteria Induce Skin Regeneration via IL-1β Signaling” Cell Host & Microbe, 2021, 29, 1–15
  26. Cecillia Lui, Alexander Chin, Seungman Park, Yang Bai, Enoch Yeung, Chulan Kwon, Gordon Tomaselli, Yun Chen, Narutoshi Hibino, “Mechanical stimulation enhances the development of scaffold-free, 3D-printed, engineered heart tissue grafts” Journal of Tissue Engineering and Regenerative Medicine, 2021, 15:503–512
  27. Seungman Park, Wei-Hung Jung, Matthew Pittman, Junjie Chen, Yun Chen, “The effects of stiffness, viscosity, and geometry of microenvironment in homeostasis, aging and diseases” Journal of Biomechanical Engineering, 2020, 142(10), 100804
  28. Seungman Park, Yu Shi, Myung Hyun Jo, Taekjip Ha, Li-Fan Lu, Daniel Reich, Yun Chen, “Force-dependent trans-endocytosis by breast cancer cells depletes costimulatory receptor CD80 and attenuates T cell activation” Biosensors and Bioelectronics, 2020, 165(1), 112389
  29. Zhenhui Liu, Se Jong Lee, Seungman Park, Konstantinos Konstantopoulos, Kristine Glunde, Yun Chen, Ishan Barman, “Cancer cells display increased migration and deformability in pace with metastatic progression” FASEB Journal, 2020, 34(7), 9307-9315
  30. Seungman Park, Yoon Ki Joo, Yun Chen, “Versatile and high-throughput force measurement platform for dorsal cell mechanics” Scientific Reports, 2019, 9, 13826
  31. Seungman Park, Jiaxiang Tao, Li Sun, Chen-Ming Fan, Yun Chen, “Economic, modular and portable skin viscoelasticity measurement device for in situ longitudinal studies” Molecules, 2019, 24(5), 907
  32. Seungman Park, Cecillia Lui, Wei‐Hung Jung, Debonil Maity, Chin Siang Ong, Joshua Bush, Venkat Maruthamuthu, Narutoshi Hibino, Yun Chen, “Mechanical characterization of hiPSCs-derived cardiac tissues for quality control” Advanced Biosystems, 2018, 2(12), 1800251 (Editor’s selection for the issue on World Heart Day)
  33. Seungman Park, Yoon Ki Joo, Yun Chen, “Dynamic adhesion characterization of cancer cells under blood flow-mimetic conditions: effects of cell shape and orientation on drag force” Microfluidics&Nanofluidics, 2018, 22, 108
  34. Seungman Park*, “Computational modeling for prediction of the shear stress of three-dimensional isotropic and aligned fiber networks” Computer Methods and Programs in Biomedicine, 2017, 148, p. 91-98
  35. Seungman Park*, “Fluid-structure interaction analysis for drug transport in a curved stenotic right coronary artery” Journal of Biosciences and Medicines, 2016, 4, p. 105-115
  36. Seungman Park, Angela Seawright, Sinwook Park, Craig Dutton, Fred Grinnell, Bumsoo Han, “Preservation of tissue microstructure and functionality during freezing by modulation of cytoskeletal structure” Journal of the Mechanical Behavior of Biomedical Materials, 2015, 45: p. 32-44
  37. Seungman Park, Catherine Whittington, Sherry Voytik-Harbin, Bumsoo Han, “Microstructural parameter-based modeling for transport properties of collagen matrices” Journal of Biomechanical Engineering,2015, 137: p. 061003
  38. Seungman Park*, “A computational prediction for the effective treatment of human airway burns” Computer Methods in Biomechanics and Biomedical Engineering, 2015, p. 1-11
  39. Basma Ibrahim, Seungman Park, Bumsoo Han, Yoon Yeo, “A strategy to deliver genes to cystic fibrosis lungs: A battle with environment” Journal of Controlled Release, 2011, 155(2): p. 289-295
  40. Seungman Park, Young Uk Min, Myung Jin Kang, Kyung Chun Kim, Ho Seong Ji, “In vitro hemodynamic study on the stenotic right coronary artery using experimental and numerical analysis” Journal of Mechanics in Medicine and Biology, 2010, 10(4): p. 695-712

List of Book and Book Chapters

  1. Nikita Gopakumar, Abdulla M Ali, Sumayah Oudda, Amarnath Singam, Seungman Park, “3D-Bioprinted Skin Tissues for Improving Wound Healing: Current Status and Perspective”, Advances in Experimental Medicine and Biology, 1-17, Springer, 2024
  2. Seungman Park, Yun Chen, “Measurement of Forces for Trans-Endocytosis at Dorsal and Ventral Sides of the Cell”, The Immune Synapse: Methods and Protocols, 327-343, Springer, 2023
  3. Sumayah Oudda, Abdulla M Ali, Anna L. Chien, Seungman Park, “Leveraging Tissue Engineering for Skin Cancer Models”, Cell Biology and Translational Medicine, Vol 19, Springer, 2022
  4. Seungman Park, Yun Chen, “Mechanics of Biological Systems: Introduction to Mechanobiology and Experimental Techniques”, A Morgan & Claypool publication as part of IOP Concise Physics, 2019

    https://iopscience.iop.org/book/978-1-64327-392-1
  5. Soham Ghosh, Seungman Park, Bumsoo Han, “Freezing-Induced Changes of Extracellular Matrix and Functional Properties of Engineered Tissues” in Multiscale Technologies for Cryomedicine: Implementation from Nano to Macroscale, World Scientific, 2016
css.php